Epithalon (also spelled Epitalon) is a synthetic tetrapeptide — four amino acids (Ala-Glu-Asp-Gly) — developed from Epithalamin, a natural peptide extract of the pineal gland. First researched by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology, Epithalon has been studied for over 35 years and is one of the most researched longevity peptides in existence.
Bangkok Peptide Center supplies Epithalon in 10mg lyophilised vials for laboratory research use. Each vial is third-party tested at 99%+ purity with Certificate of Analysis available on request.
About Epithalon
Epithalon’s primary mechanism of interest in research involves its effects on telomerase — the enzyme responsible for maintaining telomere length. Telomeres are the protective caps on the ends of chromosomes that shorten with each cell division, and their progressive shortening is one of the most studied biological hallmarks of aging. Research has shown that Epithalon can activate telomerase and stimulate telomere elongation in cell culture models — a finding that has attracted significant attention from the longevity research community.
Beyond telomerase activation, Epithalon has been studied for its effects on the pineal gland, melatonin production, antioxidant activity, and immune function across decades of primarily Russian research — much of which has more recently been translated and reviewed by Western researchers.
Research applications
- Telomere biology — telomerase activation and telomere length studies
- Cellular senescence and replicative aging models
- Pineal gland function and melatonin regulation research
- Antioxidant activity — studies showing increased SOD and catalase activity
- Immune system modulation — effects on T-cell activity in aged models
- Circadian rhythm regulation research
- Oncology research — studies examining effects on tumour models
- Lifespan extension research in animal models
The telomere connection
Epithalon’s most discussed research property is its relationship with telomerase and telomere biology. Published studies have shown Epithalon can induce telomerase activity in human somatic cells — cells that do not normally express telomerase — and produce measurable telomere elongation. This has made it one of the most referenced compounds in anti-aging and longevity research circles, alongside compounds like NAD+ and GHK-Cu.
It is worth noting that the majority of foundational Epithalon research originates from Russian institutions, and while a growing body of independent research has validated many findings, researchers should review the available literature at PubMed when designing research protocols.
Epithalon and the longevity stack
Epithalon is frequently studied alongside other longevity-focused compounds. Bangkok Peptide Center supplies a comprehensive range for combination research:
- NAD+ 500mg — cellular energy and sirtuin activation
- GHK-Cu 50mg — collagen synthesis and gene expression
- MOTS-C 10mg — mitochondrial metabolic regulation
Product specifications
Contents
10mg Epithalon lyophilised powder per vial
Purity
≥99% — third-party verified
Storage
Cool, dry place away from light. Refrigerate after reconstitution. Use within 28 days.
Included
Free bacteriostatic water and needles with every order
Delivery
Same-day delivery across Bangkok for orders placed before 12pm. Nationwide express available across Thailand. All orders dispatched in plain, unbranded packaging every day of the week. See our shipping page for full details.
For laboratory research purposes only. Epithalon supplied by Bangkok Peptide Center is not a medicine, not an approved pharmaceutical product, and is not intended to diagnose, treat, cure, or prevent any disease. Not for human consumption.




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